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A novel proteoglycan synthesized and secreted by chondrocytes of the superficial zone of articular cartilage. Immunodetection and partial c DNA sequence of the proteoglycan, superficial zone protein, synthesized by cells lining synovial joints. Most of the joints in the body are synovial joints.
Let's look at the knee joint in more detail as it can be classed as a typical synovial joint. Inside the knee joint there are two bones joined together: the femur and tibia. The ends of the bones are covered in a very smooth layer of a tough, rubbery substance known as cartilage. The joint is enclosed in a stiff and elastic capsule made of strong, fibrous tissue. The joint capsule completely encloses the space around the joint surfaces and is lined by a synovial membrane.
Synovial Fluid Analysis. What is a synovial fluid analysis? The tests usually include the following: An exam of physical qualities of the fluid, such as its color and thickness Chemical tests to check for changes in the fluid's chemicals Microscopic analysis to look for crystals, bacteria, and other substances Other names: joint fluid analysis. What is it used for? Causes of joint problems include: Osteoarthritis , the most common form of arthritis.
It is a chronic, progressive disease that causes joint cartilage to break down. It can be painful and lead to loss of mobility and function. Gout , a type of arthritis that causes inflammation in one or more joints, usually in the big toe Rheumatoid arthritis , a condition in which the body's immune system attacks healthy cells in your joints Joint effusion , a condition that happens when too much fluid builds up around a joint.
It often affects the knee. When it affects the knee, it may be referred to as knee effusion or fluid on the knee. Infection in a joint Bleeding disorder , such as hemophilia. Hemophilia is an inherited disorder that can cause excessive bleeding.
Sometimes the excess blood ends up in the synovial fluid. Why do I need a synovial fluid analysis? You may need this test if you have symptoms of a joint disorder. These include: Joint pain Joint swelling Redness at a joint Joint that feels warm to the touch. What happens during a synovial fluid analysis? During the procedure: A health care provider will clean the skin on and around the affected joint.
If your child is getting the procedure, he or she may also be given a sedative. Sedatives are medicines that have a calming effect and help reduce anxiety. Once the needle is in place, your provider will withdraw a sample of synovial fluid and collect it in the syringe of the needle.
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